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产品编号:D293065
产品名称:6'-Desmethyl-6'-methylhydroxy Etoricoxib-β-glucuronide
产品CAS:349536-40-9
规格含量:5mg
产品价格:面议
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产品详细介绍
标准品编号:
D293065
名称:
6'-Desmethyl-6'-methylhydroxy Etoricoxib-β-glucuronide
别名:
(2S,3S,4S,5R,6R)-6-((5-Chloro-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridin]-6'-yl)methoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid; [5-Chloro-3-[4-(methylsulfonyl)phenyl][2,3'-bipyridin]-6'-yl]methyl β-D-Glucopyranosiduronic Acid;
CAS号:
349536-40-9
分子式:
C₂₄H₂₃ClN₂O₉S
分子量:
550.97
种类:
Standards; Enzyme Activators and Inhibitors;
应用:
6'-Desmethyl-6'-methylhydroxy Etoricoxib-β-glucuronide is a metabolite of Etoricoxib (E934100), which is a specific inhibitor of cyclooxygenase-2 (COX-2) enzyme.
参考文献
McGeer, P.L., et al.: Exp. Gerontol., 37, 925 (2002); Chenevard, R., et al.: Circulation, 107, 405 (2003); Rodrigues, D., et al.: Drug Metab. Dispos., 31, 224 (2003);