((2R,4S)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenes__C376655

产品基本信息

产品编号：C376655

产品名称：((2R,4S)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenes

产品CAS：

规格含量：250mg

产品价格：面议

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产品详细介绍

标准品编号:	C376655
名称:	((2R,4S)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate
分子式:	C₁₈H₁₇Cl₃O₅S
外观:	Colourless Oil
分子量:	451.75
溶解度:	DCM, Ethyl Acetate, Methanol
类别:	Building Blocks; Chiral Molecules;
应用:	((2R,4S)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate is an intermediate in the synthesis of Itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal.
参考文献	Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)

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