产品基本信息
产品编号：D434410
产品名称：7-O-2,2-Dichloroethoxycarbonyl Docetaxel
产品CAS：158810-72-1
规格含量：5mg
产品价格：面议
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产品详细介绍
标准品编号:
D434410
名称:
7-O-2,2-Dichloroethoxycarbonyl Docetaxel
别名:
(αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxybenzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-4-[[(2,2-dichloroethoxy)carbonyl]oxy]-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; [2aR-[2aα,4β,4aβ,6β,9α(αR,βS*),11α,12α,12aα,12bα]]- β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxybenzenepropanoic Acid 12b-(Acetyloxy)-12-(benzoyloxy)-4-[[(2,2-dichloroethoxy)carbonyl]oxy]-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete Benzenepropanoic Acid Deriv.
CAS号:
158810-72-1
分子式:
C₄₆H₅₅Cl₂NO₁₆
分子量:
948.83
种类:
Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
7-O-2,2-Dichloroethoxycarbonyl Docetaxel is a metabolite of Docetaxel (D494420); an antineoplastic and antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin.
参考文献
Ringel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991); Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)
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