Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
(2R,4R)-1-Boc-N-Fmoc-4-amino-pyrrolidine-2-carboxylic Acid can be used as reactant/reagent in synthetic preparation of KMI-008 peptide derivatives and proline-based peptidomimetic analogs and determination of their activity as BACE1 inhibitors (β-secretase inhibitors). It can also be used as reagent/reactant for preparation of aminoproline residues for solid phase synthesis of integrin binding cyclic peptides by bromination, azidation and protection/deprotection protocol.
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