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产品基本信息
产品编号：B382030
产品名称：(1R,4S)-(R)-Bicalutamide Sulfide Camphanic Acid Ester
产品CAS：113299-39-1
规格含量：500mg
产品价格：面议
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产品详细介绍
标准品编号:
B382030
名称:
(1R,4S)-(R)-Bicalutamide Sulfide Camphanic Acid Ester
别名:
[1R-[1α(R*),4β]]-4,7,7-Trimethyl-3-oxo-1-[[[4-cyano-3-(trifluoromethyl)phenyl]amino]carbonyl]-2-[(4-fluorophenyl)thio]-1-methylethyl Ester 2-Oxabicyclo[2.2.1]heptane-1-carboxylic Acid; (1R,4S)-(R)-1-((4-Cyano-3-(trifluoromethyl)phenyl)amino)-3-((4-fluorophenyl)thio)-2-methyl-1-oxopropan-2-yl 4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylate
CAS号:
113299-39-1
分子式:
C₂₈H₂₆F₄N₂O₅S
分子量:
578.58
类别:
Building Blocks; Miscellaneous;
应用:
(1R,4S)-(R)-Bicalutamide Sulfide Camphanic Acid Ester is an intermediate in the synthesis of (R)-Bicalutamide (B382005), the (R)-enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).
文献
Tucker, H., et al.: J. Med. Chem., 31, 954 (1988); Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990); Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993); McKillop, D., et al.: Xenobiotica, 25, 623 (1995)
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