Building Blocks; Isotopic Labeled Analogues; Miscellaneous;
应用:
4-(4-Amino-3-fluorophenoxy)-N-(methyl-d3)-2-pyridinecarboxamide is an intermediate for the synthesis of Regorafenib-d3 (R143002), which is the isotope labelled analog of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM and is useful for the treatment of inflammation. Also an anti-proliferative agent.
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