Building Blocks; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
应用:
N-(2,3-Dimethoxybenzyl)homopiperonylamine-d6 is a useful synthetic intermediate in the synthesis of Berberine Hydrochloride-d6 (B318152); the isotope labelled analog of Berberine Hydrochloride (B318150) which is an isoquinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.