2-(1,3-dioxolan-2-ylmethyl)-1H-isoindole-1,3(2H)-dione is an intermediate used in the synthesis of 2-(Aminomethyl)-1,3-dioxolane (A633583), which is a useful reactant for the preparation of non-zwitterionic aryl sulfonamides as Nav1.7 inhibitors for improved membrane permeability.