tert-Butyl ((2R,3S,4E,8Z)-1,3-Dihydroxyoctadeca-4,8-dien-2-yl)carbamate is an intermediate in the synthesis of (4E, 8Z)-Sphingadienine-C18-1-phosphate (S680655), which is a sphingoid base of sea cucumber cerebroside that may have cytotoxicity activity against human colon cancer cells.