Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Labelled Chaetomellic Acid A (C291815). It is an alkyl dicarboxylic acid isolated from the fermentation of Chaetomella acutiseta. Chaetomellic acid A has been shown to be a potent, highly specific inhibitor of RAS farnesyl protein transferase (FPTase). ÂThe association between RAS proteins and cancer has made Chaetomellic acid A a potential chemotherapeutic agent.
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