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产品基本信息
产品编号：V314500
产品名称：Vinflunine Ditartrate
产品CAS：194468-36-5
规格含量：10mg
产品价格：面议
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产品详细介绍
标准品编号:
V314500
名称:
Vinflunine Ditartrate
别名:
(2β,3β,4β,5α,12β,19α)-4-(Acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methylaspidospermidine-3-carboxylic Acid Methyl Ester (2R,3R)-2,3-Dihydroxybutanedioate; 4'-Deoxy-20',20'-difluoro-5'-nor- vincaleukoblastine Ditartrate; 20',20'-Difluoro-3',4'-dihydrovinorelbine Ditartrate; BMS 710485; F 12158; Javlor;
CAS号:
194468-36-5
参考CAS号:
162652-95-1-free base
分子式:
C₅₃H₆₆F₂N₄O₂₀
外观:
白色至Light Beige Solid
熔点:
>207˚C (dec)
分子量:
1117.1
储存:
-20°C Freezer
溶解度:
DMSO (Slightly), Methanol (Slightly)
类别:
Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Vinflunine is a semisynthetic Vinca alkaloid with microtubule destabilizing and antiangiogenic activity. Vinflunine is a derivative of Vinorelbine. Vinflunine is used as an antineoplastic.
参考文献
Kruczynski, A., et al.: Crit. Rev. Oncol. Hematol., 40, 159 (2001), Fabre, C., et al.: Biochem. Pharmacol., 64, 733 (2002), Bennouna, J. et al.: Ann. Oncol., 14, 630 (2003), Bennouna, J., et al.: Expert Opin. Invest. Drugs, 14, 1259 (2005).
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