Standards; Amino Acids; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
N-[(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester Mixture is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
您的位置：![N-[(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester (Mixture)](/uploads/allimg/191212/1_12121S03I9A.png "N-[(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester (Mixture)")
