7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; LEE 011A; Ribociclib
CAS号:
1211441-98-3
分子式:
C₂₃H₃₀N₈O
外观:
Beige Solid
熔点:
>180°C (dec.)
分子量:
434.54
储存:
-20°C Freezer
溶解度:
DMSO (Slightly), Methanol (Slightly)
种类:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
LEE 011 can be used in biological study of kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer.
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