[4S-[4R*,7S*,8R*,9R*,13Z,16R*(E)]]-4,8-Dihydroxy-5,5,7,9-tetramethyl-16-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-oxacyclohexadec-13-ene-2,6-dione; (4S,7R,8S,9S,13Z,16S)-4,8-Dihydroxy-5,5,7,9-tetramethyl-16-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]oxacyclohexadec-13-ene-2,6-dione; (-)-Deoxyepothilone A; (-)-Desoxyepothilone A; Desoxyepothilone A; Epo C
CAS号:
186692-73-9
分子式:
C₂₆H₃₉NO₅S
分子量:
477.66
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Epothilone C is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant.
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