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产品基本信息
产品编号：I809017
产品名称：Ibufenac-13C6
产品CAS：
规格含量：5mg
产品价格：面议
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产品详细介绍
标准品编号:
I809017
名称:
Ibufenac-13C6
别名:
4-(2-Methylpropyl)benzeneacetic Acid-13C6; 4-(2-Methylpropyl)phenylacetic Acid-13C6; 4-Isobutoxyphenylacetic Acid-13C6; 4-Isobutylphenylacetic Acid-13C6; Dytransin-13C6; Ibunac-13C6; Medirex-13C6; NSC 99976-13C6
参考CAS号:
1553-60-2
分子式:
C₆¹³C₆H₁₆O₂
分子量:
198.21
溶解度:
Dichloromethane; Diethyl Ether; Ethyl Acetate; THF
种类:
Standards; Isotopic Labeled Analogues;
应用:
Ibufenac-13C6 is an intermediate in synthesizing Ibuprofen-13C6 (I140003), a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
参考文献
Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)
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