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产品基本信息
产品编号：F462470
产品名称：N-9H-Fluoren-2-yl-N-hydroxy-acetamide
产品CAS：53-95-2
规格含量：10mg
产品价格：面议
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产品详细介绍
标准品编号:
F462470
名称:
N-9H-Fluoren-2-yl-N-hydroxy-acetamide
别名:
N-Fluoren-2-yl-N-hydroxy-acetamide; N-Fluoren-2-yl-acetohydroxamic Acid; 2-(N-Hydroxyacetamido)fluorene; N-2-Fluorenyl-N-hydroxyacetamide; N-2-Fluorenylacetohydroxamic Acid; N-Acetyl-N-2-fluorenylhydroxylamine; N-Hydroxy-2-(acetylamino)fluorene; N-Hydroxy-AAF; N-Hydroxy-N-(2-fluorenyl)acetamide; NSC 46522;
CAS号:
53-95-2
分子式:
C₁₅H₁₃NO₂
外观:
Light Yellow to Yellow Solid
熔点:
140-143°C
分子量:
239.27
储存:
冰箱保存
溶解度:
DMSO (Slightly), Methanol (Slightly)
种类:
Standards; Enzyme Activators and Inhibitors;
应用:
N-9H-Fluoren-2-yl-N-hydroxy-acetamide inactivates human arylamine N-acetyltransferases (NATs), NAT1 and NAT2. Mutagenicity examined in Salmonella typhimurium TA1538. Liver produced metabolite of the cancinogen 2-Acetamidofluorene (A158535), which is also a highly carcinogenic compound.
参考文献
Liu, Li., et al.: Chem. Res. Toxicol., 22, 1962-1974 (2009); Inami, K., et al.: Genes Env., 30, 71-76 (2008); Ames, B., et al.: Proc. Nat. Acad. Sci. U. S.A., 70, 2281 (1973); Verna, L., et al.: Pharmacol. Ther., 71, 83 (1996);
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