对照品 > 标准物质 > 环保部标准物质 >
产品基本信息
产品编号：D231270
产品名称：N-De[2-(methylsulfonyl)ethyl] Lapatinib
产品CAS：697299-82-4
规格含量：50mg
产品价格：面议
联系我们:
产品详细介绍
标准品编号:
D231270
名称:
N-De[2-(methylsulfonyl)ethyl] Lapatinib
别名:
6-[5-(Aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-4-quinazolinamine; [6-(5-Aminomethylfuran-2-yl)quinazolin-4-yl][3-chloro- 4-(3-fluorobenzyloxy)phenyl]amine;
CAS号:
697299-82-4
分子式:
C₂₆H₂₀ClFN₄O₂
外观:
Light Yellow to Light Beige Solid
熔点:
>141ºC (dec.)
分子量:
474.91
储存:
-20°C Freezer, Under inert atmosphere
溶解性:
DMSO (Slightly), Methanol (Slightly, Heated)
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.
参考文献
He, K., et al.: Chem. Res. Toxicol., 11, 252 (1998), Rusnuk, D., et al.: Cancer Res., 61, 7196 (2001), Li, X., et al.: Drug Metab. Dispos., 37, 1242 (2009),
您的位置：![N-De[2-(methylsulfonyl)ethyl] Lapatinib](/uploads/allimg/191121/1_112116232O2I.png "N-De[2-(methylsulfonyl)ethyl] Lapatinib")
