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| 产品基本信息 |
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| 产品编号：H805180 |
| 产品名称：(S)-1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-aminium Chloride |
| 产品CAS： |
| 规格含量：10mg |
| 产品价格：面议 |
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| 产品详细介绍 |
| 标准品编号: |
H805180 |
| 名称: |
(S)-1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-aminium Chloride |
| 分子式: |
C₁₄H₂₁ClN₂O₃ |
| 分子量: |
300.78 |
| 种类: |
Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: |
(S)-1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-aminium Chloride is an intermediate used in the synthesis of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide (H805105), which is an impurity of bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway. |
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