Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
(αR,γS)-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic acid α-ethyl Ester is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.