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产品基本信息
产品编号：C175985
产品名称：(S)-(-)-Carbidopa
产品CAS：28860-95-9
规格含量：50mg
产品价格：面议
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产品详细介绍
标准品编号:
C175985
名称:
(S)-(-)-Carbidopa
别名:
(αS)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic Acid; (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinamic Acid; (S)-Carbidopa; 1-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic Acid; Carbidopa; HMD; Hydrazino-α-methyldopa; L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic Acid; L-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic Acid; L-α-Methyl-β-(3,4-dihydroxyphenyl)-α-hydrazinopropionic Acid; L-α-Methyldopahydrazine; Lodosin; Lodosyn; MK 486; N-Aminomethyldopa; α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic Acid; α-Methyldopahydrazine;
CAS号:
28860-95-9
参考CAS:
Monohydrate: 38821-49-7
分子式:
C₁₀H₁₄N₂O₄
外观:
白色至白色固体
熔点:
>181°C (dec.)
分子量:
226.23
储存:
Hygroscopic, 冰箱保存, under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
稳定性:
Unstable in Solution
类别:
Standards; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
(S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA (D533751) for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle.
参考文献
Henry, G.M. et al.: Psychosom. Med., 38, 95 (1976); Leguire, L.E. et al.: Invest. Ophthalmol. Vis. Sci. 34, 3090 (1993); Deleu, D. et al.: Naun. Schmied. Arch. Pharmacol. 348: 576 (1993);
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