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N-Boc Acetaminophen-cysteine
产品基本信息
产品编号:B602753
产品名称:N-Boc Acetaminophen-cysteine
产品CAS:
规格含量:50mg
产品价格:面议
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产品详细介绍
标准品编号: B602753
名称: N-Boc Acetaminophen-cysteine
别名: (R)-3-((4-Acetamidophenyl)thio)-2-((tert-butoxycarbonyl)amino)propanoic Acid
分子式: C₁₆H₂₂N₂O₅S
外观: 白色固体
分子量: 354.42
溶解度: Methanol
类别: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用: N-Boc Acetaminophen-cysteine is an intermediate in the synthesis of Acetaminophen-cysteine (A161255). Acetaminophen-cysteine is a metabolite of Acetaminophen (A161220) and a serum biomarker of acetaminophen exposure (1,2). Acetaminophen-cysteine can be used to identify acetaminophen-induced acute liver failure when standard testing is inconclusive. Acetaminophen is oxidized by cytochrome P450 to a reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI), which can react with cysteine residues of hepatic proteins to yield Acetaminophen-cysteine (3).
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